Name: Malgorzata Czyz, Prof., PhD
Title: professor
Department: Molecular Biology of Cancer
Address: 6/8 Mazowiecka Street
e-mail: malgorzata.czyz@umed.lodz.pl
Office telephone: +48-426784277
Areas of research interests comprise the field of gene regulation on transcriptional level (Nucleic Acids Res 1993; J Biol Chem 1995; Eur J Biochem 1999; Blood 2004), DNA-drug interactions (Z. Naturforsch 2001; Curr Med Chem 2003; Biochem Pharmacol 2005), and induction of differentiation and apoptosis in cancer cells (Eur J Pharmacol 2004; ABP 2007; Biochem Pharmacol 2005, 2007, 2008; J Inorganic Biochem 2008; Cancer Chemother & Pharmacol 2008; Eur J Pharmacol 2008; Br J Pharmacol 2009; Melanoma Res 2009).
Recent papers:
Lesiak K, Koprowska K, Zalesna I, Nejc D, Düchler M, Czyz M: Parthenolide, a sesquiterpene lactone from the medical herb Feverfew, shows anti-cancer activity against human melanoma cells in vitro. Melanoma Research, in press
Sztiller-Sikorska M., Jakubowska J., Wozniak M., Stasiak M., Czyz M.: A non-apoptotic function of caspase-3 in pharmacologically induced differentiation of K562 cells (2009) British Journal of Pharmacology; 157: 1451-1462
Czyz M, Jakubowska J & Sztiller-Sikorska M.: STI571/doxorubicin concentration-dependent switch for diverse caspase actions in CML cell line K562" (2008) Biochemical Pharmacology, 75:1761-1773
Szulawska A., Arkusinska J., Czyz M.: Accumulation of y-globin mRNA and induction of irreversible erythroid differentiation after treatment of CML cell line K562 with new doxorubicin derivatives (2007) Biochemical Pharmacology; 73,175-184
Sources of founding: national
Number of PhD positions available: 1
Clinical PhD positions available: no